Steroids and derivatives
Cayman Chemical Resolvin D2 Neurochemicals
A product of the action of 15- and 5-LO on DHA; dampens excessive neutrophil trafficking to sites of inflammation; reduces zymosan-stimulated PMN infiltration by 70% at 10 pg per mouse; reduces PAF-stimulated leukocyte adherence and emigration at 1 nM; stimulates nitric oxide production decreases leukocyte-endothelial interactions; reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance in a mouse model of sepsis
BIOHIPPO AAV-D2-mCherry-WPRE-bGH-polyA
Recombinant adeno associated virus expressing mCherry under the D2 promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Cayman Chemical LnolIn VItamIn D3 1g
A biologically inactive precursor to calcitriol converted to active metabolites in vivo; obtained from dietary sources, including fish, or formed in the epidermis via photolytic conversion of 7-dehydro cholesterol to previtamin D3 by UVB radiation, followed by isomerization to vitamin D3; can be converted to 25-hydroxy vitamin D3 in the liver by CYP2R1 before being converted to calcitriol by CYP27B1 in the kidney
Medchemexpress LLC HY-15264 1mg Medchemexpress, MC 1046 CAS:126860-83-1 Purity:>98%
Medchemexpress, HY-15264 1mg MC 1046 CAS:126860-83-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Paeonol-d3 | 55712-78-2 | 10 MG
Paeonol-d3 is a deuterium-labeled analogue of paeonol used as a tracer and internal standard in drug development and pharmacokinetic and metabolic studies. It is supplied as a powder and is suitable for quantitative analyses where isotopic labeling is required.
- Deuterium-labeled compound for tracer studies.
- Useful as an internal standard in quantitative analyses.
- Provided as a powder for convenient handling and storage.
- Available in small research pack sizes, such as 10 mg.
- Stable under recommended storage conditions for long-term use.
Medchemexpress LLC Skatole-d3 | 111399-60-1 | 134.19 | 1 MG
Skatole-d3 is the deuterium labeled Skatole. It is produced by intestinal bacteria and regulates intestinal epithelial cellular functions by activating aryl hydrocarbon receptors and p38. It is for research use only. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 1-Methyladenine-d3 | 15763-06-1 | 284.29 | 10 MG
1-Methyladenosine-d3 is the deuterium-labeled version of 1-Methyladenosine. 1-Methyladenosine is an RNA modification that can act as a tumor marker, with elevated levels linked to cancer development. The methylation of 1-methyladenosine leads to the upregulation of PPARδ expression, which regulates cholesterol metabolism and activates the Hedgehog signaling pathway, thereby promoting liver tumorigenesis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS.
- Deuteration is used in drug molecules primarily as tracers for quantitation during drug development.
- Has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical 5 6-trns-VItamIn D3 10mg
An isomer of vitamin D3; increases tibia ash weight and bone mineralization in vitamin D-deficient chicks at 1, 3, and 10 UG/day; induces intestinal calcium transport and bone calcium mobilization in anephric rats fed a low-calcium and vitamin D-deficient diet at 25 UG/animal
Medchemexpress LLC Deapi-platycodin D3 | 67884-05-3 | 1 ML
Deapi-platycodin D3 is a triterpenoid saponin derived from the roots of Platycodon grandiflorum. This compound is intended for research use only.
- Purity: 98.86%
- Molecular weight: 1255.35
- Formula: C58H94O29
- Appearance: White to off-white solid
- Classification: Terpenoids, triterpenes
- Initial source: Plants, Campanulaceae, Platycodon grandiflorus (Jacq.) A. DC.
- Storage (solid): 4°C, protect from light
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month (protect from light)
- Solubility (in vitro): DMSO 100 mg/mL (79.66 mM)
Medchemexpress LLC 4-Pyridoxic acid-d3 | 1435934-03-4 | 98.8% | 186.18 | 1 MG
4-Pyridoxic acid-d3 is the deuterium labeled 4-Pyridoxic acid, which is a catabolic product of vitamin B6 and is excreted in the urine.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 7-methylguanosine-d3 | 00-00-0 | 98.5% | 301.29 g·mol⁻¹ | C11H13D3N5O5 | 5 MG
7-Methylguanosine-d3 is a deuterium-labeled stable isotope of 7-methylguanosine intended as a high-purity reference standard for analytical and biochemical applications. It is supplied in small-mass packages suitable for use in quantitative mass spectrometry, tracer studies, and method development. The unlabeled parent compound has reported activity against cNIIIB nucleotidase (IC50 = 87.8 ± 7.5 μM).
- High-purity deuterium-labeled isotopic standard for accurate mass spectrometry.
- Suitable as an internal standard for LC-MS or GC-MS quantitation.
- Useful for tracer studies and metabolic labeling experiments.
- Provided in small mass vials compatible with analytical workflows.
- Molecular formula C11H13D3N5O5; molecular weight 301.29 g·mol⁻¹.
Cayman Chemical 25hydroxy VItamIn D3 3 3am 5mg
A vitamin D3 analog; contains a highly reactive amine group that can be coupled to a sepharose matrix for affinity purification of vitamin D binding protein; inhibits 25-hydroxy vitamin D3-1α-hydroxylase